The toll from China's coronavirus epidemic jumped to 1,868 on Tuesday after 98 more people died, according to the National Health Commission.

Nearly 72,500 people nationwide have been infected by the new COVID-19 strain of the virus, which first emerged in December before spiralling into a nationwide epidemic.

There were 1,886 new cases reported Tuesday — a decline on Monday's figure, and the lowest single-day figure of new cases so far this month.

Most of the deaths were in Hubei province, the hard-hit epicentre of the outbreak, with five reported elsewhere in the country.

Hubei has been locked down to try to contain the virus, with tens of millions of people placed under effective quarantine in the province.

The number of new cases reported outside Hubei province was just 79, down from 890 on February 4.

It marks the lowest number of new cases outside the virus-struck province since January 23.

China's national health authority has said the declining numbers are a sign that the outbreak is under control.

However, World Health Organization chief Tedros Adhanom Ghebreyesus said the trend "must be interpreted very cautiously".

"Trends can change as new populations are affected. It is too early to tell if this reported decline will continue. Every scenario is still on the table," he told reporters on Monday.

Chinese health officials have urged patients who recovered from the coronavirus to donate blood so that plasma can be extracted to treat others who are critically ill.

Plasma from patients who have recovered from a spell of pneumonia triggered by COVID-19 contains antibodies that can help reduce the virus load in critically ill patients, an official from the National Health Commission told a press briefing Monday.

More than 12,000 people have recovered and been discharged, according to health commission figures.

China asks recovered patients to donate plasma for virus treatment
Beijing (AFP) Feb 17, 2020 –

Chinese health officials Monday urged patients who have recovered from the coronavirus to donate blood so that plasma can be extracted to treat others who are critically ill.

Drugmakers are racing to develop a vaccine and treatment for the epidemic, which has killed 1,770 people and infected over 70,500 people across China.

Plasma from patients who have recovered from a spell of pneumonia triggered by COVID-19 contains antibodies that can help reduce the virus load in critically ill patients, an official from China's National Health Commission told a press briefing Monday.

"I would like to make a call to all cured patients to donate their plasma so that they can bring hope to critically ill patients," said Guo Yanhong, who heads the NHC's medical administration department.

Eleven patients at a hospital in Wuhan — the epicentre of the disease — received plasma infusions last week, said Sun Yanrong, of the Biological Center at the Ministry of Science and Technology.

"One patient (among them) has already been discharged, one is able to get off the bed and walk and the others are all recovering," she said.

The call comes days after China's state-owned medical products maker reported successful results from its trial at Wuhan First People's Hospital.

China National Biotec Group Co. said in a post on its official WeChat account that severely ill patients receiving plasma infusions "improved within 24 hours".

The World Health Organization said exploring the use of plasma as a treatment for the novel coronavirus was "important", but cautioned it needed to be done "with safety".

"It is a very important area of discovery," head of WHO's emergencies programme Michael Ryan told reporters in Geneva, pointing out that plasma had proven effective in saving lives when combatting a range of different diseases.

"It is a very valid way to explore therapeutics, especially when we don't have vaccines and we don't have specific anti-virals," he said.

His colleague Sylvie Briand, who heads WHO's Global Infectious Hazard Preparedness division, meanwhile cautioned that plasma-based treatments could be difficult to scale up to reach large numbers of patients, and stressed the need to carefully follow safety protocols.

"With blood products you can also transmit other diseases, so the protocol … is very important," she told reporters.

Sun stressed that "clinical studies have shown that infusing plasma (from recovered patients) is safe and effective."

Blood donors will undergo a test to ensure that they are not carrying the virus, said Wang Guiqiang, chief physician at Peking University First Hospital.

"Only plasma is taken, not all the blood," he said.

"Other components of the blood including red blood cells and platelets will be infused back into the donors."